TY - JOUR AU - Michel, Loren AU - Benezra, Robert AU - Díaz Rodríguez, María Elena PY - 2004 UR - http://hdl.handle.net/10366/167928 AB - [EN]The failure of cell cycle regulatory checkpoints is a common event in human cancer. Defects at the G(1)-S transition have been widely characterized, but only more recently has aberrant checkpoint signaling during mitotic progression been... LA - eng KW - Mad2, Mitotic checkpoint, microtubules, essential gene, multi-nucleation, Cyclin B, securin KW - Mad2 KW - Mitotic checkpoint KW - microtubules KW - Essential gene KW - Multi-nucleation KW - Cyclin B KW - Securin KW - Apoptosis KW - Animals KW - Humans KW - Cell Cycle Proteins KW - Nuclear Proteins TI - MAD2 dependent mitotic checkpoint defects in tumorigenesis and tumor cell death: a double edged sword T2 - Cell cycle VL - 3 M2 - 990 ER -