TY  - JOUR 
AU  - Díaz Rodríguez, María Elena
AU  - Sotillo, Rocio
AU  - Schvartzman, Juan-Manuel
AU  - Benezra, Robert
PY  - 2008
UR  - http://hdl.handle.net/10366/167952
AB  - [EN]Hec1 (Highly Expressed in Cancer 1) is one of four proteins of the outer kinetochore Ndc80 complex involved in the dynamic interface between centromeres and spindle microtubules. Its overexpression is seen in a variety of human tumors and...
LA  - eng
KW  - Aneuploidy
KW  - Cancer
KW  - Chromosome instability
KW  - Kinetochores
KW  - Mitosis
KW  - Chromosomal Instability
KW  - Doxycycline
KW  - Microtubule-Associated Proteins
KW  - Gene Expression Regulation
KW  - Aneuploidy
KW  - Neoplasms
KW  - Nuclear Proteins
KW  - Tissue Distribution
KW  - Animals
KW  - Cell Cycle Proteins
KW  - Mice
TI  - Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo
DO  - 10.1073/pnas.0803504105
T2  - Proceedings of the National Academy of Sciences of the United States of America
VL  - 105
M2  - 16719
ER  -