TY  - JOUR 
AU  - Ríos-Luci, Carla
AU  - Domínguez-Kelly, Raquel
AU  - León, Leticia G
AU  - Díaz Rodríguez, María Elena
AU  - Freire, Raimundo
AU  - Pandiella Alonso, Atanasio
AU  - Cikotiene, Inga
AU  - Padrón, José M
PY  - 2011
SN  - 0960-894X
UR  - http://hdl.handle.net/10366/167984
AB  - [EN]A Phenotypic Drug Discovery strategy was applied to study a set of pyrimidine analogs prepared by means of intramolecular oxidation-reduction reactions of N-substituted-N-(2,6-disubstituted-5-nitro-4-pyrimidinyl)aminoacetic acid methyl esters in...
LA  - eng
KW  - Phenotypic Drug Discovery
KW  - Antitumor agents
KW  - Cell cycle
KW  - Mitotic arrest
KW  - Structure–activity relationships
KW  - Drug Discovery
KW  - Pyrimidines
KW  - Structure-Activity Relationship
KW  - Cell Cycle
KW  - Oxidation-Reduction
KW  - Humans
KW  - Anaphase
KW  - Cell Line
KW  - Antineoplastic Agents
KW  - Metaphase
KW  - Neoplasms
TI  - A modular approach to trim cellular targets in anticancer drug discovery
DO  - 10.1016/j.bmcl.2011.09.069
T2  - Bioorganic & medicinal chemistry letters
VL  - 21
M2  - 6641
ER  -