TY  - JOUR 
AU  - Robles Valero, Javier
AU  - Fernández-Nevado, Lucía
AU  - Cuadrado López, Myriam
AU  - Lorenzo Martín, Luis Francisco
AU  - Fernández-Pisonero, Isabel
AU  - Abad, Antonio
AU  - Redín, Esther
AU  - Montuenga, Luis
AU  - Martín-Zanca, Dionisio
AU  - Bigas, Anna
AU  - Mallo, Moisés
AU  - Dosil Castro, Mercedes
AU  - Bustelo, Xosé R.
PY  - 2022
SN  - 1574-7891
UR  - http://hdl.handle.net/10366/168603
AB  - [EN]Mutations in the VAV1 guanine nucleotide exchange factor 1 have been recently found in peripheral T cell lymphoma and nonsmall-cell lung cancer (NSCLC). To understand their pathogenic potential, we generated a gene-edited mouse model that...
LA  - eng
PB  - FEBS and Wiley
KW  - RAC1
KW  - TP53
KW  - Angioimmunoblastic T cell lymphoma
KW  - Follicular helper T cells
KW  - Nonsmall-cell lung cancer
KW  - Peripheral T cell lymphoma
KW  - Proto-Oncogene Proteins p21(ras)
KW  - Mutant Proteins
KW  - Mutation
KW  - Animals
KW  - Proto-Oncogene Proteins c-vav
KW  - Neoplasms
KW  - Mice
TI  - Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model
DO  - 10.1002/1878-0261.13295
T2  - Molecular Oncology
VL  - 16
M2  - 3533
ER  -