TY  - JOUR 
AU  - Cuadrado, Myriam
AU  - Robles Valero, Javier
PY  - 2021
SN  - 2079-7737
UR  - http://hdl.handle.net/10366/168652
AB  - [EN]Guanosine nucleotide exchange factors (GEFs) are responsible for catalyzing the transition of small GTPases from the inactive (GDP-bound) to the active (GTP-bound) states. RHO GEFs, including VAV proteins, play essential signaling roles in a wide...
LA  - eng
PB  - MDPI
KW  - NFAT
KW  - NOTCH1
KW  - PTCL
KW  - RAC1
KW  - RHO GEFs
KW  - T-ALL
KW  - VAV proteins
KW  - Lung cancer
KW  - Mouse models
KW  - Oncogene
KW  - Signaling
KW  - Tumor suppressor
KW  - Proto-Oncogene Proteins c-vav
KW  - Hematologic Neoplasms
TI  - VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles
DO  - 10.3390/biology10090888
T2  - Biology
VL  - 10
ER  -