TY  - JOUR 
AU  - Ojeda, Virginia
AU  - Robles Valero, Javier
AU  - Barreira, María
AU  - Bustelo, Xosé R.
PY  - 2015
UR  - http://hdl.handle.net/10366/168733
AB  - [EN]Coronin 1A (Coro1A) is involved in cytoskeletal and signaling events, including the regulation of Rac1 GTPase- and myosin II-dependent pathways. Mutations that generate truncated or unstable Coro1A proteins cause immunodeficiencies in both humans...
LA  - eng
KW  - Coronin 1A
KW  - Rac1 GTPase
KW  - peripheral T-cell-deficient (Ptcd) mouse
KW  - Actin cytoskeleton
KW  - Immunodeficiency
KW  - Cell Culture Techniques
KW  - Mutation
KW  - HEK293 Cells
KW  - Animals
KW  - Humans
KW  - Signal Transduction
KW  - Cytoskeleton
KW  - Actin Cytoskeleton
KW  - COS Cells
KW  - Mice
KW  - Microfilament Proteins
TI  - The disease-linked Glu-26-Lys mutant version of Coronin 1A exhibits pleiotropic and pathway-specific signaling defects
DO  - 10.1091/mbc.E15-01-0052
T2  - Molecular biology of the cell
VL  - 26
M2  - 2895
ER  -