TY - JOUR AU - Fernández Parejo, Natalia AU - Lorenzo Martín, Luis Francisco AU - García-Pedrero, Juana M AU - Rodrigo, Juan P AU - Dosil Castro, Mercedes AU - Bustelo, Xosé R. PY - 2024 UR - http://hdl.handle.net/10366/168979 AB - [EN]VAV2 is an activator of RHO GTPases that promotes and maintains regenerative proliferation-like states in normal keratinocytes and oral squamous cell carcinoma (OSCC) cells. Here, we demonstrate that VAV2 also regulates ribosome biogenesis in... LA - eng PB - Springer KW - Ribosome synthesis KW - Oral squamous cell carcinoma KW - RHO GTPases KW - VAV2 KW - Keratinocytes KW - RNA Polymerase I KW - Carcinoma KW - Mouth Neoplasms KW - Humans KW - Proto-Oncogene Proteins c-vav KW - rho GTP-Binding Proteins KW - Cell Proliferation TI - VAV2 orchestrates the interplay between regenerative proliferation and ribogenesis in both keratinocytes and oral squamous cell carcinoma DO - 10.1038/s41598-024-54808-0 T2 - Scientific reports VL - 14 M2 - 4060 ER -