TY  - JOUR 
AU  - Minello, Anna
AU  - Gómez Escudero, Jesús
AU  - Sridhara, Sreerama Chaitanya
AU  - Martín, Charlotte
AU  - Girard, Elodie
AU  - Martínez Cañas, Juan Carlos
AU  - Memari, Yasin
AU  - Bustos, Maria Rose
AU  - Galarreta, Antonio
AU  - Boucherit, Virginie
AU  - Imyanitov, Evgeny
AU  - Bodvarsdottir, Sigridur Klara
AU  - Baulande, Silvain
AU  - Vicent Salomon, Anne
AU  - Servant, Nicolas
AU  - Altmeyer, Matthias
AU  - Sigurdsson, Stefan
AU  - Stoppa-Lynnet, Dominique
AU  - Nik-Zainal, Serena
AU  - Carreira, Aurora
PY  - 2025
UR  - http://hdl.handle.net/10366/169033
AB  - [EN]Germline monoallelic truncating mutations in BRCA2, a key mediator of homologous recombination (HR), predispose individuals to breast and ovarian cancer. Tumorigenesis is typically attributed to biallelic inactivation, yet evidence suggests...
LA  - eng
PB  - Nature Research
KW  - Cancer
KW  - Instability
KW  - Breast
KW  - BRCA2
KW  - NFKB
KW  - Mutations
KW  - CRISPR
KW  - Breast
KW  - Mutation
TI  - A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription
DO  - 10.1038/S41467-025-67209-2
T2  - Nature Communications
VL  - 16
ER  -