TY - JOUR AU - Escribano-Lopez, Irene AU - Díaz Morales, Noelia AU - Iannantuoni, Francesca AU - Lopez-Domenech, Sandra AU - de Marañon, Aranzazu M AU - Abad-Jimenez, Zaida AU - Bañuls, Celia AU - Rovira-Llopis, Susana AU - Herance, Jose R AU - Rocha, Milagros AU - Victor, Victor M PY - 2018 UR - http://hdl.handle.net/10366/169700 AB - [EN]There is growing focus on mitochondrial impairment and cardiovascular diseases (CVD) in type 2 diabetes (T2D), and the development of novel therapeutic strategies in this context. It is unknown whether mitochondrial-targeting antioxidants such as... LA - spa PB - Nature Research (Springer Nature) KW - Sirtuina 1 (SIRT1) KW - Diabetes tipo 2 KW - Antioxidante mitocondrial (SS-31) KW - Interacción leucocito-endotelio KW - Estrés oxidativo KW - Inflamación KW - Sirtuin 1 (SIRT1) KW - Type 2 diabetes KW - Mitochondrial antioxidant (SS-31) KW - Leukocyte-endothelium interaction KW - Oxidative stress KW - Inflammation KW - Diabetes Mellitus, Type 2 KW - Antioxidants KW - Oxidative Stress KW - Sirtuin 1 KW - Mitochondria TI - The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes DO - 10.1038/s41598-018-34251-8 T2 - Scientific Reports VL - 8 ER -