TY  - JOUR 
AU  - Díaz Rodríguez, María Elena
AU  - Pandiella Alonso, Atanasio
PY  - 2016
UR  - http://hdl.handle.net/10366/170905
AB  - [EN]The use of thalidomide derivatives (IMIDs) has improved multiple myeloma prognosis, through an unknown mechanism of action. Recently one molecular target, the cereblon (CRBN) protein, has been identified. CRBN acts by binding to DDB1-CUL4-ROC1...
LA  - eng
PB  - Taylor and Francis Group
KW  - CRBN
KW  - Cancer
KW  - IMIDs
KW  - Myeloma
KW  - Thalidomide
KW  - Cell Cycle
KW  - DNA-Binding Proteins
KW  - Gene Expression Regulation
KW  - Humans
KW  - Ubiquitin-Protein Ligases
KW  - Multiprotein Complexes
KW  - Cytosol
KW  - Cell Line
KW  - Antineoplastic Agents
KW  - Cell Proliferation
KW  - Multiple Myeloma
KW  - Apoptosis
KW  - Peptide Hydrolases
KW  - Thalidomide
KW  - Protein Binding
TI  - Modulation of cereblon levels by anti-myeloma agents
DO  - 10.3109/10428194.2015.1037752
T2  - Leukemia & Lymphoma
VL  - 57
M2  - 167
ER  -