TY - JOUR AU - Hernández Sánchez, Alberto AU - González, Teresa AU - Sobas, Marta AU - Sträng, Eric AU - Castellani, Gastone AU - Abáigar, María AU - Valk, Peter J M AU - Villaverde Ramiro, Ángela AU - Benner, Axel AU - Metzeler, Klaus H AU - Azibeiro, Raúl AU - Tettero, Jesse M AU - Martínez-López, Joaquín AU - Pratcorona, Marta AU - Martínez Elicegui, Javier AU - Mills, Ken I AU - Thiede, Christian AU - Sanz, Guillermo AU - Döhner, Konstanze AU - Heuser, Michael AU - Haferlach, Torsten AU - Turki, Amin T AU - Reinhardt, Dirk AU - Schulze-Rath, Renate AU - Barbus, Martje AU - Hernández Rivas, Jesús María AU - Huntly, Brian AU - Ossenkoppele, Gert AU - Döhner, Hartmut AU - Bullinger, Lars PY - 2024 UR - http://hdl.handle.net/10366/172057 AB - [EN]Balanced rearrangements involving the KMT2A gene (KMT2Ar) are recurrent genetic abnormalities in acute myeloid leukemia (AML), but there is lack of consensus regarding the prognostic impact of different fusion partners. Moreover, prognostic... LA - eng KW - Leukemia, Myeloid, Acute KW - Myeloid-Lymphoid Leukemia Protein KW - Histone-Lysine N-Methyltransferase KW - Mutation KW - Chromosomes, Human, Pair 11 KW - Humans KW - Middle Aged KW - Prognosis KW - Adult KW - Female KW - Male KW - Aged KW - Young Adult KW - Translocation, Genetic KW - Gene Rearrangement KW - Adolescent KW - Aged, 80 and over KW - Survival Rate KW - High-Throughput Nucleotide Sequencing KW - Aged KW - Chromosomes KW - Young Adult KW - Leukemia KW - Adult KW - Humans KW - Adolescent KW - Middle Aged KW - Prognosis KW - Mutation KW - High-Throughput Nucleotide Sequencing KW - Gene Rearrangement KW - Myeloid-Lymphoid Leukemia Protein KW - Histone-Lysine N-Methyltransferase KW - Survival Rate TI - Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study DO - 10.1038/s41375-024-02333-4 T2 - Leukemia VL - 38 M2 - 1929 ER -