TY - JOUR AU - Lorenzo Martín, Luis Francisco AU - Hübscher, Tania AU - Bowler, Amber D. AU - Broguiere, Nicolas AU - Langer, Jakob AU - Tillard, Lucie AU - Nikolaev, Mikhail AU - Radtke, Freddy AU - Lutolf, Matthias P. PY - 2024 SN - 0028-0836 UR - http://hdl.handle.net/10366/172697 AB - [EN]Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of both tumour and microenvironmental structures1-3. This has enabled better modelling of low-complexity... LA - eng PB - Nature Research KW - Colorectal cancer KW - Tissue engineering KW - Organ-on-a-chip KW - Tumor Microenvironment KW - Optogenetics KW - Time Factors KW - Tissue Engineering KW - Colon KW - Colorectal Neoplasms KW - Animals KW - Drug Evaluation, Preclinical KW - Organoids KW - Mice KW - Light TI - Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo DO - 10.1038/s41586-024-07330-2 T2 - Nature VL - 629 M2 - 450 ER -