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Titel
Parvalbumin immunoreactivity during the development of the cerebellum of the rainbow trout
Autor(es)
Schlagwort
Calcium
Cerebellum
Development
Fish
Parvalbumin
Purkinje cells
Clasificación UNESCO
2490 Neurociencias
2490.02 Neuroquímica
Fecha de publicación
1998-08-08
Verlag
Elsevier
Citación
Porteros A, Arévalo R, Briñón JG, Crespo C, Aijón J, Alonso JR. Parvalbumin immunoreactivity during the development of the cerebellum of the rainbow trout. Brain Res Dev Brain Res. 1998 Aug 8;109(2):221-7
Zusammenfassung
The distribution of parvalbumin immunoreactivity in the developing cerebellum ofthe rainbow trout was studied by using a specific monoclonal antibody and the avidin-biotin peroxidase method. Parvalbumin immunoreactivity was absent during the embryonic development of the cerebellum. The first immunoreactive elements, identified by their localization and posterior morphological evolution as immature Purkinje cells, appeared at 6
days posthatching in the presumptive corpus cerebelli and lobus vestibulolateralis. The
labeling extended throughout the cerebellum following a caudorostral gradient, and in 21
days alevins, parvalbumin immunoreactive Purkinje cells were also observed in the valvula cerebelli. The appearance of PV-immunostaining in the Purkinje cells was not simultaneous; the labeling was observed initially in the cell body, extending gradually to the dendritic branches and finally to the axon. From one year onwards, parvalbumin immunoreactive terminal puncta from the Purkinje cell axons were observed surrounding the cell bodies of eurydendroid cells, that were parvalbumin immunonegative in all developmental stages studied. The spatio-temporal pattern of parvalbumin immunoreactivity in the rainbow trout
cerebellum is different to previous observations in the cerebellum of amniotes.
URI
DOI
http://dx.doi.org/10.1016/S0165-3806(98)00085-6
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