| dc.contributor.author | Novo Veleiro, Ignacio | |
| dc.contributor.author | Cieza Borrella, Clara Isabel | |
| dc.contributor.author | Pastor Encinas, Isabel | |
| dc.contributor.author | Chamorro Fernández, Antonio Javier | |
| dc.contributor.author | Laso Guzmán, Francisco Javier | |
| dc.contributor.author | González Sarmiento, Rogelio | |
| dc.contributor.author | Marcos Martín, Miguel | |
| dc.date.accessioned | 2017-09-21T08:53:48Z | |
| dc.date.available | 2017-09-21T08:53:48Z | |
| dc.date.issued | 2016 | |
| dc.identifier.citation | Novo-Veleiro, I., Cieza-Borrella, C., Pastor, I., Chamorro A.-J., Laso, F.-J., González-Sarmiento, R., et al. (2016) A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men. PLoS ONE 11(12): e0168685. | es_ES |
| dc.identifier.issn | 1932-6203 | |
| dc.identifier.uri | http://hdl.handle.net/10366/135283 | |
| dc.description.abstract | [EN[Genetic polymorphisms in the RAS gene family are associated with different diseases, which may include alcohol-related disorders. Previous studies showed an association of the allelic variant rs26907 in RASGRF2 gene with higher alcohol intake. Additionally, the rs61764370 polymorphism in the KRAS gene is located in a binding site for the let-7 micro- RNA family, which is potentially involved in alcohol-induced inflammation. Therefore, this study was designed to explore the association between these two polymorphisms and susceptibility to alcoholism or alcoholic liver disease (ALD). | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Public Library of Science (New York) | es_ES |
| dc.rights | Attribution-NonCommercial-NoDerivs 4.0 International | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Molecular medicine (genetics and pathology) | es_ES |
| dc.subject | Single Nucleotide Polymorphism | es_ES |
| dc.subject | Alcoholic Liver Cirrhosis | es_ES |
| dc.subject | Polimorfismo genético | es_ES |
| dc.subject | Cirrosis hepática | es_ES |
| dc.title | A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men | es_ES |
| dc.type | info:eu-repo/semantics/article | es_ES |
| dc.relation.publishversion | https://doi.org/10.1371/journal.pone.0168685 | |
| dc.identifier.doi | 10.1371/journal.pone.0168685 | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
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