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Título
Nitric Oxide and Respiratory Helminthic Diseases
Autor(es)
Assunto
Nitric Oxide
Respiratory Helminthic Diseases
Clasificación UNESCO
3205.08 Enfermedades Pulmonares
3207.12 Parasitología
Fecha de publicación
2010
Editor
Hindawi Publishing Corporation (London, United Kingdom)
Citación
Muro, A., Pérez-Arellano, J.L. (2010). Nitric Oxide and Respiratory Helminthic Diseases. Journal of Biomedicine and Biotechnology: London: Hindawi Pub.
Resumo
[EN]Nitric oxide (NO) is a very simple molecule that displays very important functions both in helminths (mainly those involved
in respiratory pathology) and in mammalian hosts. In this paper we review four issues related to interaction of NO and lung
helminthic diseases. Firstly, we evaluated data available on the NO synthesis and release by helminths and their biological role.
Next, we summarized the effect of antigens obtained from different phases of the biological cycle on NO production by host
mammalian cells (mainly from human sources). Thirdly, we revised the evaluation of NO on the biological activities and/or the
viability of respiratory helminths. Lastly, the deleterious consequences of increased production of NO during helminthic human
infection are detailed.
URI
ISSN
1110-7243
DOI
10.1155/2010/958108
Versión del editor
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