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Titel
Epidemiological impact of Alzheimer’s disease and other dementias in the Spanish-Portuguese border region
Autor(es)
Schlagwort
Alzheimer's disease
Epidemiology
Fecha de publicación
2021-12-31
Verlag
Alzheimer's Association
Citación
Alonso-Sardón, M., Martín-Delgado, M. A., Pérez-Martín, R.N., González Ortega, E., & NEUROQUALYFAM group (2021) Epidemiological impact of Alzheimer’s disease and other dementias in the Spanish-Portuguese border region. Alzheimer´s & Dementia, 17(s10), e052028. https://doi.org/10.1002/alz.052028
Resumen
Background: Dementia has reached epidemic proportions and become a huge Public
Health problem. Alzheimer’s disease (AD) is the most common type of dementia. In
Spain, more than 800,000 people suffer from AD (Spanish Society of Neurology-SEN).
Age is the main risk marker for developing this disease. Its prevalence is three times
higher in women than in men due to females’ higher life expectancy. The aim is to know
the epidemiological profile and quantify the current scope of the ADand other dementias
in the rural Spanish-Portuguese border area, one of the most depopulated and
aging regions in Europe.
Method: A cross-sectional descriptive study was designed to estimate the prevalence
of persons diagnosed with an ICD-9-CM or ICD-10 code diagnosis of dementia in ten
BasicHealth Areas of the cross-border rural area of province of Salamanca, Spain, during
June-July 2020 (39,354 inhabitants). The cases were recorded from the Electronic
Clinical Record of Primary Care (MEDORA) by the Regional Health Management of
Castilla y León.
Result: A total of 579 individuals suffer some type of dementia in the Spanish-
Portuguese border region, with a predominance of females (70%) vs. males (30%), and
an age range of 38 to 109 years (Figure_1). AD was diagnosed in 307(53%) persons
and other dementias in 272(47%). Gender distribution of the diagnoses is different
in women and men (p<0.001) (Table_1). The mean(±SD) age was 85.2±7.6 years for
women and 82.5±8.7 years for men (p<0.001). The mean(±SD) age of Alzheimert’s
patients was lower, 83.7±7.1 vs. 85.2±8.9 (p=0.031) (Figure_2). The global prevalence
of dementia was 1.47 per 100 inhabitants (0.78% in AD vs. 0.69% in other dementias).
The prevalence of dementia was 2.12% in females and 0.85% in males. Prevalence
range in the ten Basic Health Areas: from 2.98 (La-Alberca) to 0.77 (Tamames) per 100
inhabitants. 26.4% of people with AD and other dementias in this region were institutionalized.
Conclusion: The prevalence data obtained confirm that AD and other dementias must
be considered a public health problem in the rural Spanish-Portuguese border region
that represents a significant deterioration in the quality of life (QoL) in patients and
their families.
URI
ISSN
2352-8737 (online)
DOI
10.1002/alz.052028
Versión del editor
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