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Título
Ferrocene-Decorated Phenol Derivatives by Trapping ortho-Quinone Methide Intermediates with Ferrocene
Autor(es)
Fecha de publicación
2018
Resumen
The InCl3-catalyzed reaction of ferrocene with ortho-hydroxybenzyl alcohols is reported and represents a convenient route for the synthesis of ferrocenyl phenols. This carbon–carbon bond forming process is believed to proceed through an ortho-quinone methide intermediate that can be intercepted by ferrocene through a Friedel–Crafts-type process. Preliminary cytotoxic screening carried out on several cancer cell lines revealed that some of the compounds exhibit moderate cytotoxicity.
URI
ISSN
1434-193X
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