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dc.contributor.author | García Ortiz, Luis | |
dc.contributor.author | Recio Rodríguez, José Ignacio | |
dc.contributor.author | Mora Simón, Sara Pilar | |
dc.contributor.author | Guillaumet, John | |
dc.contributor.author | Marti, Ruth | |
dc.contributor.author | Agudo Conde, Cristina | |
dc.contributor.author | Rodríguez Sánchez, Emiliano | |
dc.contributor.author | Maderuelo Fernández, José Ángel | |
dc.contributor.author | Ramos-Blanes, Rafel | |
dc.contributor.author | Gómez Marcos, Manuel Ángel | |
dc.date.accessioned | 2024-03-21T11:52:49Z | |
dc.date.available | 2024-03-21T11:52:49Z | |
dc.date.issued | 2016 | |
dc.identifier.uri | http://hdl.handle.net/10366/156878 | |
dc.description.abstract | [ENG]Background: There is limited evidence concerning the relationship between vascular disease and health-related quality of life (HRQL). We investigated the relationship between vascular structure and function with health-related quality of life in a population with intermediate cardiovascular risk. Methods: This study analyzed 303 subjects with ankle-brachial index (ABI) values ranging from 0.9 to 1.4 who were included in the MARK study (age 35 to 74 years; mean:60.5 ±8.5), of which 50.2 % were women. Measurements included: ABI, brachial-ankle pulse wave velocity (ba-PWV), and cardio-ankle vascular index (CAVI), all measured using the VaSera device. The central augmentation index was adjusted to 75 lpm (AIx_75) using the Mobil-O-Graph device. HRQL was assessed by the Spanish version of the SF-12, version2. The highest obtained CAVI and ba-PWV values and the lowest ABI values were considered for the study. Results: The cohort was composed of21 % smokers, 76 % hypertensive patients, and 24 % diabetic patients. The ABI mean was 1.09±0.07,the ba-PWV mean was 14.64±2.55 m/s with a 12.9 % of subjects higher than 17.5 m/s, AIx_75 26.46 ± 14.05, and CAVI 8.61 ± 1.08 with a 36.6 % of subjects higher than 9. Men scored higher than women in the HRQL measurements for physical (PSC-12; 49.9 vs. 46.9, p = 0.004) and mental (MSC-12) domains (51.2 vs. 47.7, p=0.003). Age was positively correlated with CAVI (r = 0.547), ba-PWV (r = 0.469), AIx_75 (r = 0.255, p < 0.01), and the MSC-12 (r =0.147, p<0.05), but not the PSC-12. In the adjusted multiple linear regression analysis, the positive association of ABI and CAVI with the PSC-12 was maintained. Conclusions: The ABI in the normal range has a positive association with the PSC-12 of HRQL evaluated with the SF-12. The CAVI also showed a positive association with the PSC-12 of HRQL. Trial Registration: ClinicalTrials.gov Identifier: NCT01428934. | es_ES |
dc.format.mimetype | application/pdf | |
dc.language.iso | eng | es_ES |
dc.subject | Health-related quality of life | es_ES |
dc.subject | Arterial stiffness | es_ES |
dc.subject | Ankle-brachial index | es_ES |
dc.subject | Brachial ankle pulse wave velocity | es_ES |
dc.subject | Cardio-ankle vascular index | es_ES |
dc.subject | Augmentation index | es_ES |
dc.title | Vascular structure and function and their relationship with health-related quality of life in the MARK study | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.identifier.doi | 10.1186/s12872-016-0272-9 | |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.identifier.essn | 1471-2261 | |
dc.journal.title | BMC Cardiovascular Disorders | es_ES |
dc.volume.number | 16 | es_ES |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es_ES |