TY  - JOUR 
AU  - Gallego-Yerga, Laura
AU  - Ochoa, Rodrigo
AU  - Lans, Isaías
AU  - Peña-Varas, Carlos
AU  - Alegría-Arcos, Melissa
AU  - Cossio, Pilar
AU  - Ramírez, David
AU  - Peláez, Rafael
PY  - 2021
SN  - 2001-0370
UR  - http://hdl.handle.net/10366/148381
AB  - Tubulin is a well-validated target for herbicides, fungicides, anti-parasitic, and anti-tumor drugs. Many of the non-cancer tubulin drugs bind to its colchicine site but no colchicine-site anticancer drug is available. The colchicine site is composed...
LA  - eng
KW  - Ensemble pharmacophore
KW  - Virtual screening
KW  - Tubulin
KW  - Colchicine
KW  - Drug design
KW  - Antimitotic
TI  - Application of ensemble pharmacophore-based virtual screening to the discovery of novel antimitotic tubulin inhibitors
DO  - 10.1016/j.csbj.2021.07.039
T2  - Computational and Structural Biotechnology Journal
VL  - 19
M2  - 4360
ER  -