TY - JOUR AU - Clavaín, Laura AU - Fernández-Pisonero, Isabel AU - Movilla, Nieves AU - Lorenzo-Martín, L Francisco AU - Nieto, Blanca AU - Calera Abad, José Antonio AU - Garcia Navas, Rosula Mercedes AU - Llorente González, Clara AU - Sánchez Martín, Manuel Adolfo AU - Vicente Manzanares, Miguel AU - Santos de Dios, Eugenio Miguel AU - Alarcón, Balbino AU - García-Aznar, José M AU - Dosil Castro, Mercedes AU - Bustelo, Xosé R. PY - 2023 SN - 0950-9232 UR - http://hdl.handle.net/10366/156737 AB - [EN]The R-RAS2 GTP hydrolase (GTPase) (also known as TC21) has been traditionally considered quite similar to classical RAS proteins at the regulatory and signaling levels. Recently, a long-tail hotspot mutation targeting the R-RAS2/TC21 Gln72 residue... LA - eng PB - Springer Nature KW - Monomeric GTP-Binding Proteins KW - Neoplasms KW - Humans KW - Cell line KW - Ras proteins KW - Signal transduction KW - Monomeric GTP-Binding Proteins KW - Humans KW - Signal Transduction KW - Cell Line KW - ras Proteins KW - Neoplasms TI - Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors DO - 10.1038/s41388-022-02563-9 T2 - Oncogene VL - 42 M2 - 389 ER -