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dc.contributor.authorNovo Veleiro, Ignacio
dc.contributor.authorCieza Borrella, Clara Isabel
dc.contributor.authorPastor Encinas, Isabel
dc.contributor.authorChamorro Fernández, Antonio Javier 
dc.contributor.authorLaso Guzmán, Francisco Javier 
dc.contributor.authorGonzález Sarmiento, Rogelio 
dc.contributor.authorMarcos Martín, Miguel 
dc.date.accessioned2017-09-21T08:53:48Z
dc.date.available2017-09-21T08:53:48Z
dc.date.issued2016
dc.identifier.citationNovo-Veleiro, I., Cieza-Borrella, C., Pastor, I., Chamorro A.-J., Laso, F.-J., González-Sarmiento, R., et al. (2016) A Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Men. PLoS ONE 11(12): e0168685.es_ES
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10366/135283
dc.description.abstract[EN[Genetic polymorphisms in the RAS gene family are associated with different diseases, which may include alcohol-related disorders. Previous studies showed an association of the allelic variant rs26907 in RASGRF2 gene with higher alcohol intake. Additionally, the rs61764370 polymorphism in the KRAS gene is located in a binding site for the let-7 micro- RNA family, which is potentially involved in alcohol-induced inflammation. Therefore, this study was designed to explore the association between these two polymorphisms and susceptibility to alcoholism or alcoholic liver disease (ALD).es_ES
dc.language.isoenges_ES
dc.publisherPublic Library of Science (New York)es_ES
dc.rightsAttribution-NonCommercial-NoDerivs 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectMolecular medicine (genetics and pathology)es_ES
dc.subjectSingle Nucleotide Polymorphismes_ES
dc.subjectAlcoholic Liver Cirrhosises_ES
dc.subjectPolimorfismo genéticoes_ES
dc.subjectCirrosis hepáticaes_ES
dc.titleA Single Nucleotide Polymorphism in the RASGRF2 Gene Is Associated with Alcoholic Liver Cirrhosis in Menes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.relation.publishversionhttps://doi.org/10.1371/journal.pone.0168685
dc.identifier.doi10.1371/journal.pone.0168685
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses_ES


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Attribution-NonCommercial-NoDerivs 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 4.0 International