Mostrar el registro sencillo del ítem
dc.contributor.author | Pérez González, David | |
dc.contributor.author | Malmierca, Manuel S. | |
dc.contributor.author | Moore, J. M. | |
dc.contributor.author | Hernández, Olga | |
dc.contributor.author | Covey, Ellen | |
dc.date.accessioned | 2023-12-20T11:16:47Z | |
dc.date.available | 2023-12-20T11:16:47Z | |
dc.date.issued | 2006-02-01 | |
dc.identifier.citation | Pérez-González, D., Malmierca, M. S., Moore, J. M., Hernández, O., & Covey, E. (2006). Duration selective neurons in the inferior colliculus of the rat: topographic distribution and relation of duration sensitivity to other response properties. Journal of neurophysiology, 95(2), 823–836. | es_ES |
dc.identifier.issn | 0022-3077 | |
dc.identifier.uri | http://hdl.handle.net/10366/153970 | |
dc.description.abstract | [EN]Many animals use duration to help them identify the source and meaning of a sound. Duration-sensitive neurons have been found in the auditory midbrain of mammals and amphibians, where their selectivity seems to correspond to the lengths of species-specific vocalizations. In this study, single neurons in the rat inferior colliculus (IC) were tested for sensitivity to sound duration. About one-half (54%) of the units sampled showed some form of duration selectivity. The majority of these (76%) were long-pass neurons that responded to sounds exceeding some duration threshold (range: 5-60 ms). Band-pass neurons, which only responded to a restricted range of durations, made up 13% of duration-sensitive neurons (best durations: 15-120 ms). Other units displayed short-pass (2%) or mixed (9%) response patterns. The majority of duration-sensitive neurons were localized outside the central nucleus of the IC, especially in the dorsal cortex, where more than one-half of the neurons sampled had long-pass selectivity for duration. Band-pass duration tuned neurons were only found outside the central nucleus. Characteristics of duration-sensitive neurons in the rat support the idea that this filtering arises through an interaction of excitatory and inhibitory inputs that converge in the IC. Band-pass neurons typically responded at sound offset, suggesting that their tuning is created through the same mechanisms that have been described in echolocating bats. The finding that the first-spike latencies of all long-pass neurons were longer than the shortest duration to which they responded supports the idea that they receive transient inhibition before, or simultaneously with, a sustained excitatory input. The ranges of selectivity in rat IC neurons are within the range of durations of rat vocalizations. These data suggest that a population of neurons in the rat IC have evolved to transmit information about behaviorally relevant sound durations using mechanisms that are common to all mammals, with an emphasis on long-pass tuning characteristics. | es_ES |
dc.description.sponsorship | Spanish Ministry of Science and Education Grant BFI-2003-09147-02-01 National Institute of Deafness and Other Communication Disorders Grant DC-00607 | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | American Physiological Society | es_ES |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Duration tuning | es_ES |
dc.subject | Sound duration | es_ES |
dc.subject | Auditory midbrain | es_ES |
dc.subject | Filtering properties | es_ES |
dc.subject.mesh | Auditory Diseases, Central | * |
dc.title | Duration selective neurons in the inferior colliculus of the rat: topographic distribution and relation of duration sensitivity to other response properties | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.subject.unesco | 2411.13 Fisiología de la Audición | es_ES |
dc.identifier.doi | 10.1152/jn.00741.2005 | |
dc.relation.projectID | BFI-2003-09147-02-01 | es_ES |
dc.relation.projectID | DC-00607 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |
dc.subject.decs | enfermedades auditivas centrales | * |