| dc.contributor.advisor | González Sarmiento, Rogelio | |
| dc.contributor.advisor | Caloca Roldán, Maria José | |
| dc.contributor.author | Barrio Real, Laura | |
| dc.date.accessioned | 2011-04-05T12:35:09Z | |
| dc.date.available | 2011-04-05T12:35:09Z | |
| dc.date.issued | 2011 | |
| dc.identifier.uri | http://hdl.handle.net/10366/83195 | |
| dc.description.abstract | [EN]the overall objective of this study was to analyze the presence of alterations in the gene CHN2 that could be associated with the emergence and development of cancer. Searching for pathogenic gene mutations CHN2 in tumor samples different types of cancer. Analysis of gene transcript levels in cell lines cancerígenas.Estudio CHN2 mechanisms regulating CHN2 gene promoter: promoter methylation | |
| dc.description.abstract | [ES]el objetivo general de este trabajo se centró en analizar la presencia de alteraciones en el gen CHN2 que pudieran asociarse con la aparición y desarrollo de cáncer. Búsqueda de mutaciones patogénicas del gen CHN2 en muestras de tumor de distintos tipos de cáncer. Análisis de los niveles de transcripción del gen CHN2 en líneas celulares cancerígenas.Estudio de los mecanismos de regulación del promotor del gen CHN2: metilación del promotor | es_ES |
| dc.format.extent | 151 p. | |
| dc.format.mimetype | application/pdf | |
| dc.language | Español | |
| dc.language.iso | spa | es_ES |
| dc.publisher | Universidad de Salamanca | es_ES |
| dc.relation.requires | Adobe Acrobat | |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Unported | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ | |
| dc.subject | Tesis y disertaciones académicas | es_ES |
| dc.subject | Universidad de Salamanca (España) | es_ES |
| dc.subject | Academic dissertations | es_ES |
| dc.subject | Medicina | es_ES |
| dc.subject | Caracterización molecular | es_ES |
| dc.subject | Gen CHN2 | es_ES |
| dc.title | Nuevas aportaciones a la caracterización molecular del gen CHN2 | es_ES |
| dc.type | info:eu-repo/semantics/doctoralThesis | es_ES |
| dc.type | info:eu-repo/semantics/doctoralThesis | es_ES |
| dc.subject.unesco | 32 Ciencias médicas | es_ES |
| dc.identifier.doi | 10.14201/gredos.83195 | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess |
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